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Neuroinflammation in fibromyalgia and CRPS is multifactorial: Access to full-text and press release


Dr Alex Vasquez, 21 Jan 2018

Author: ​Dr Alex Vasquez

Title: Neuroinflammation in fibromyalgia and CRPS is multifactorial

JournalNature Reviews Rheumatology 12, 242 (2016)

Excerpt: "Thus, neuroinflammation in fibromyalgia and CRPS has biological contributions including gastrointestinal dysbiosis, vitamin D deficiency, and mitochondrial dysfunction. These independent contributions commonly co-exist, and each of these is additive/synergistic with the others in the promotion of peripheral and central hyperalgesia. The consistent pain-alleviating benefits of treatments for intestinal dysbiosis (antibiotics), vitamin D deficiency (supplementation) and mitochondrial dysfunction (ubiquinone) establish that these painful conditions are multifactorial and maintained by ongoing physiologic insults, each of which is treatable."


DOI/location: doi:10.1038/nrrheum.2016.25

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